The Scottish Intercollegiate Guidelines Network (SIGN) was formed in 1993. Its objective is to improve the quality of health care for patients in Scotland by reducing variation in practice and outcome, through the development and dissemination of national clinical guidelines containing recommendations for effective practice based on current evidence.
In January 2005 SIGN became part of NHS Quality Improvement Scotland (NHS QIS) and on 1st April 2011 part of Healthcare Improvement Scotland .